Effects of zonisamide monotherapy in children with epilepsy
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چکیده
منابع مشابه
Effects of zonisamide monotherapy in children with epilepsy
This study examined the efficacy and safety of zonisamide as monotherapy in pediatric patients with epilepsy. Seventy-seven children with epilepsy (ages 8 months-15 years) were treated with zonisamide. Nine patients were withdrawn early because of side effects; these patients were included in side effect but not efficacy analyses. Zonisamide dosages were initiated at approximately 2 mg/kg per d...
متن کاملzonisamide efficacy as adjunctive therapy in children with refractory epilepsy
how to cite this article: karimzadeh p, ashrafi mr, bakhshandeh bali mk, nasehi mm, taheri otaghsara sm, taghdiri mm, ghofrani m. zonisamide efficacy as adjunctive therapy in children with refractory epilepsy. iran j child neurol. 2013 spring; 7(2):37-42. objective approximately one third of epileptic children do not achieve complete seizure improvement. zonisamide is a new antiepileptic drug w...
متن کاملZonisamide Efficacy as Adjunctive Therapy in Children With Refractory Epilepsy
OBJECTIVE Approximately one third of epileptic children do not achieve complete seizure improvement. Zonisamide is a new antiepileptic drug which is effective as adjunctive therapy in treatment of intractable partial seizures. The purpose of the current study was to evaluate the effectiveness, safety, and tolerability of Zonisamide in epileptic children. MATERIALS & METHODS From November 2011...
متن کاملZonisamide monotherapy with once-daily dosing in children with cryptogenic localization-related epilepsies: clinical effects and pharmacokinetic studies
Clinical effects and pharmacokinetics of once-a-day pediatric zonisamide (ZNS) monotherapy were investigated in 72 children (range, 3 months to 15 years; mean age, 8 years and 3 months) with cryptogenic localization-related epilepsies with simple, complex, or secondarily generalized partial seizures; none had prior epilepsy treatment. ZNS was initiated at 2mg/kg; daily dosage was doubled at wee...
متن کاملLong-Term Efficacy and Safety of Zonisamide Monotherapy in Epilepsy Patients
BACKGROUND AND PURPOSE Zonisamide (ZNS) is a useful antiepileptic drug with a broad therapeutic spectrum. However, there is limited information on the long-term use of ZNS as a monotherapy. This study investigated the long-term effects of ZNS as a monotherapy for the treatment of epilepsy. METHODS We retrospectively analyzed the records of epilepsy patients treated with ZNS monotherapy at our...
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ژورنال
عنوان ژورنال: Seizure
سال: 2004
ISSN: 1059-1311
DOI: 10.1016/j.seizure.2004.04.001